Systematic reviews (SRs) are the embodiment of the evidence-based approaches, and they have reformed clinical decision-making in almost all therapy areas. The approach of SRs was essentially developed to fulfil […]
Clinical practice should ideally rely on robust scientific evidence, the standard for which are systematic reviews and meta-analyses of all randomised controlled trials (RCTs). (1,2) Therapeutic decisions in healthcare must […]
Evidence-based medicine (EBM) is gaining wide acceptance from researchers globally as it thoroughly optimizes the latest available evidence to make informed care decisions. This involves evaluating the quality of the […]
Today’s era of risk based, precision and personalized medicine demands clinical prediction models. Prediction modelling studies focus on two kinds of outcomes, viz. diagnosis (probability of a condition that is […]
Network meta-analysis (NMA) is a type of meta-analysis that adds an additional variable to a meta-analysis, and instead of a simple summation of trials that have evaluated the same treatment, […]
Every country exercises strict control on medicines’ market access. Typically, this requires successful completion and adequate presentation of results from phase I through phase III clinical trials, bringing forward the […]
Scoping reviews are exploratory projects that systematically map the literature on a topic, identifying key concepts, theories and sources of evidence. Scoping reviews are often conducted before full syntheses, and […]
Health systems have developed at different speeds, and with differing degrees of complexity throughout the twentieth century, reflecting the diverse political and social conditions in each country. Notwithstanding their diversity, […]