• Whole Health Value Assessment

    Whole Health Value Assessment
    Whole Health Value Assessment

    The focus of healthcare assessments has conventionally been more on clinical and cost-efficiency of interventions. However, this tapered focus might overlook the aspects that contribute to meaningful health outcomes among individuals. The emerging concept of “Whole Health” highlights a wider, person-centred perspective of health that goes beyond physical well-being to include behavioural, emotional, social, economic, and spiritual aspects. “Whole Health” signifies a rising consensus that value in healthcare must be taken in the context of people’s lived experiences, not only through clinical parameters, but through their ability to live well.[1, 2]
    This paradigm shift reflects in ISPOR’s Strategic Plan 2030,[3] that puts forth the concept of accessible, affordable, and more comprehensive healthcare that defines and delivers value.[3, 4] Inspired by the WHO’s renewed perspective on health as “a resource for everyday life, not the objective of living,”[5] ISPOR too identifies health as a comprehensive resource to advance HEOR. Consequently, assessments of health interventions must integrate a broader and more demonstrative belief of health aligning with the “Whole Health” paradigm.[2]
    In reality, Whole Health value assessment integrates five basic elements: it is “people-centred, comprehensive and holistic, upstream focused, equitable and accountable, and grounded in well-being.”[2] These factors define a framework where individuals, families, communities, and healthcare systems strive together to create ‘value’. An intervention’s efficacy is not reviewed only in clinical parameters but by its ability to enhance a person’s daily life, cultivate emotional and spiritual flexibility, and minimize socioeconomic challenges. Notably, the concept of “Whole Health” promotes the incorporation of clinical, behavioural, and social care systems, all working collectively to focus on the overall health demands.[2]
    The ”Whole Health” concept also encourages a more interdependent approach for generating evidence, including patient-reported outcomes (PROs), real-world data (RWD), and context-based narratives that depict different definitions of health as experienced by individuals and communities.[6] Therefore, the true health value can be assessed with components like therapeutic relationship, the patient’s personhood, and the clinician’s humanity. In Whole Health, well-being is not just the absence of disease, but the presence of a goal of contently living life and functionality, combining both hedonic (happiness-driven) and eudaimonic (meaning-driven) aspects of health.[2]
    Whole Health value assessments have significant impact on HEOR in that they broaden the scope of what is evaluated, how it is measured, and whose viewpoints are prioritized.[2] By aligning with ISPOR’s strategic goals,[3] Whole Health value assessments lead more rigorous, relevant, and unbiased evaluations that represent the complexities of ever-changing modern healthcare. Whole Health also encourages stakeholders to redefine healthcare success not only by measuring disease control or economic savings, but by evaluating the quality of life lived.[1, 2, 6]
    Whole Health value assessments encourage to perceive ‘value’ not only in the intervention, but also in its significance to what individuals sincerely need and care about. By doing so, they provide a more effective and more justified basis for healthcare decision-making globally.

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    References

    1. National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Health Care Services; Committee on Transforming Health Care to Create Whole Health: Strategies to Assess, Scale, and Spread the Whole Person Approach to Health; Meisnere M, South-Paul J, Krist AH, editors. Achieving Whole Health: A New Approach for Veterans and the Nation. Washington (DC): National Academies Press (US); 2023 Feb 15. 2, Defining Whole Health. Available from: https://www.ncbi.nlm.nih.gov/books/NBK591719/
    2. Pizzi LT, Abbott RM, Onukwugha E. Taking Health Economics and Outcomes Research Forward: Expanding the Definition of Value to Include Whole Health. Value Health. 2025; 28(5):702-704.
    3. ISPOR. Strategic Plan 2030. 2024. Available online at: https://www.ispor.org/heor-resources/news-top/news/view/2024/07/29/ispor-announces-new-strategic-plan-2030
    4. Walker J. ISPOR’s new strategic plan underscores importance of accessible, effective, efficient, and affordable global health care. Becaris Publishing. 2024. Available online at: https://becarispublishing.com/digital-content/blog-post/ispor-s-new-strategic-plan-underscores-importance-accessible-effective-efficient-and
    5. WHO. Health Promotion. Available online at: https://www.who.int/teams/health-promotion/enhanced-wellbeing/first-global-conference
    6. Westritch K. “Whole Health” Value Assessment: Universal Survey Framework for Integrating Patient Experience Data in Health Technology Assessment. National Pharmaceutical Council. 2024. Available online at: https://www.ispor.org/docs/default-source/intl2024/ispor-whole-health-value-assessment-slidesmerged.pdf?sfvrsn=4a5a66ac_0

  • EBM and HTA for Healthcare Decision Making – The Time has Come!

    EBM and HTA for Healthcare Decision Making – The Time has Come!

    Health systems have developed at different speeds, and with differing degrees of complexity throughout the twentieth century, reflecting the diverse political and social conditions in each country. Notwithstanding their diversity, all systems, however, share a common reason for their existence, namely the improvement of health for their entire populations. To attain this goal a health system undertakes a series of functions, most notably, the financing and delivering of health services.

    Since available resources are limited, delivering health services involves making decisions. Decisions are required on what interventions should be offered, the way the health system is organized, and how the interventions should be provided in order to achieve an optimal health gain with available resources, while, at the same time, respecting people’s expectations. Decision-makers thus need information about the available options and their potential consequences. It is now clear that interventions once thought to be beneficial have, in the light of more careful evaluation, turned out to be at best of no benefit or, at worst, harmful to the individual and counterproductive to the system. This recognition has led to the emergence of a concept known as “evidence-based medicine” (EBM), which argues that the information used by policymakers should be based on rigorous research to the fullest extent possible.

    Health technology assessment (HTA) increasingly plays an important role in informing reimbursement and pricing decisions and providing clinical guidance on the use of medical technologies across the world. In addition to safety and efficacy information, health economic and outcomes research (HEOR) data are also receiving expanded attention in these assessments in many countries, due to payers seeking better value for money spent on treatments. HTA is now commonly viewed as a tool to assist evidence-based health-care decisions.

    EBM has been defined as “the conscientious, explicit and judicious use of current best evidence in making decisions about the care of individual patients”. The origin of this evidence-based approach can be seen in the application of clinical medicine delivered at an individual level. Pressure to base decisions on evidence has, however, been extended to other areas of health care, such as public health interventions and health care policy-making. In this context, evidence is understood as the product of systematic observation or experiment. It is inseparable from the notion of data collection. The evidence-based approach relies mainly on research, that is, on systematically collected and rigorously analyzed data following a pre-established plan.

    There are exciting new developments in basic science that could lead to targeted, highly effective and curative treatments. Health systems are improving their electronic records and recording health outcomes, which can be analyzed using structured, sophisticated analyses in real-time. There are also new collaborative approaches between healthcare providers and technology developers to enable evaluation of technologies in the health system before adoption or early in adoption to optimize use. There is a need and an opportunity to harness these developments and improve the effectiveness and efficiency of evidence production for new health technologies to input to HTA and inform decision making. Clinicians, managers, patients, and technology developers need to be involved to ensure that the process to a coverage decision is not only efficient but that it is also effective. To be effective, health services need to be organized to enable rapid and appropriate introduction of effective technologies and disinvestment of ineffective technologies. This suggests an additional responsibility for HTA and it would involve helping technology developers understand clinical and patient needs, evidence generation requirements, and limitations and helping health systems understand the potential and implications of new technologies and possible challenges of implementation.

    Therefore, to sum everything up, the evidence should be both efficient as well as effective in order to develop more agile and adaptive processes that help to broker alignment among technology developers and health systems (including healthcare professionals and patients). This suggests that HTA needs to innovate and be prepared to play a more active role to influence evidence production and help facilitate dialogue among stakeholders to optimize technology development and use.

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