Gastric cancer is the third most common cause of cancer-related death across the world. Treatment of gastric cancer generally involves surgery followed by chemoradiation therapy or chemotherapy. Our client wanted to evaluate the safety and efficacy of commonly used chemotherapeutic medications for gastric cancer management. In order to assist our client to develop a systematic review on this topic we screened 3956 studies for 1st pass, 384 studies for 2nd pass, 6 conference abstracts (American Society of Clinical Oncology and European Society for Medical Oncology etc.) and finally we abstracted data from 45 studies.