A systematic literature review (SLR) is considered the highest form of evidence due to its rigorous approach through which every relevant piece of published or unpublished literature that is currently […]
Systematic literature reviews (SLR) are a crucial tool to identify high-quality evidence for research, policy, and practice. The success of SLRs heavily relies on the performance of the literature search […]
Clinical prediction models (CPMs) are statistical models that use patient characteristics and clinical variables to estimate the probability of a particular health outcome, such as a disease or adverse event. […]
The cost of prescription drugs is a significant burden on patients and the healthcare system, especially in countries such as the USA. High drug prices can strain government programs, such […]
Meta-analyses summarize data from head-to-head trials to evaluate pairs of treatments that have been directly compared.[1] However, in certain circumstances, multiple therapies are of interest, and no data is available […]
When seeking answers to clinical questions about efficacy or other aspects of a proposed intervention, health professionals often look for reliable evidence. Systematic literature reviews (SLRs) serve this purpose, by […]
Literature reviews play a vital role in fulfilling the primary goal of any evidence-based research by aiding in decision-making with transparent and impacting results.[1] With advances in all medical fields […]
Healthcare decisions for patients and public health policies should be supported by the best available research evidence. To ensure the hierarchy of the evidence, an evidence pyramid was conceptualized, with […]
Results from over half of all conducted randomized controlled trials (RCTs), especially those with negative or unfavorable results, never get published. This means, searching only electronic databases that index published […]