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28Sep
Automation in Evidence Synthesis: Are We There Yet?
In the ever-evolving landscape of scientific research and evidence synthesis, the demand for timely, comprehensive, and reliable information has never been greater. Decision-makers, healthcare professionals, and researchers seek up-to-the-minute insights […]
28Aug
Elevating Evidence Synthesis: Unveiling the Research Integrity Assessment (RIA) Tool
The bedrock of evidence-based decision-making rests on the integrity of systematic reviews, which rely on the credibility of the studies they encompass. While bias assessment and risk of bias evaluation […]
08Aug
Matching-Adjusted Indirect Comparisons (MAICs): What, Why, and How?
Meta-analysis is crucial in evidence-based medicine as it combines data from multiple studies for more precise treatment effect estimates. However, when head-to-head clinical trials directly comparing treatments are scarce, Indirect […]
05Jun
Collaborative Approach in Conducting Systematic Literature Reviews For Evidence Synthesis
A well-conducted systematic review and meta-analysis can be invaluable to help clinicians stay up-to-date on current evidence-based medicine.(1) However, systematic reviews and meta-analyses often tend to be highly focussed on […]
08May
Risk of Bias Assessment During Systematic Literature Reviews: Why and How?
A systematic literature review (SLR) is considered the highest form of evidence due to its rigorous approach through which every relevant piece of published or unpublished literature that is currently […]
13Apr
Using ‘Limits’ While Developing SLR Search Strategy: Advantages and Disadvantages
Systematic literature reviews (SLR) are a crucial tool to identify high-quality evidence for research, policy, and practice. The success of SLRs heavily relies on the performance of the literature search […]
10Apr
The Importance of CHARMS Checklist in the SLRs of Clinical Prediction Models
Clinical prediction models (CPMs) are statistical models that use patient characteristics and clinical variables to estimate the probability of a particular health outcome, such as a disease or adverse event. […]
31Mar
The Role and Importance of SLRs and RWE in Drug Price Negotiations in the USA
The cost of prescription drugs is a significant burden on patients and the healthcare system, especially in countries such as the USA. High drug prices can strain government programs, such […]
10Jan
An Overview of Methods for Indirect Treatment Comparisons in Healthcare Decision-making
Meta-analyses summarize data from head-to-head trials to evaluate pairs of treatments that have been directly compared.[1] However, in certain circumstances, multiple therapies are of interest, and no data is available […]