Systematic Literature Reviews

12Jan 2019

Today’s era of risk based, precision and personalized medicine demands clinical prediction models. Prediction modelling studies focus on two kinds of outcomes, viz. diagnosis (probability of a condition that is undetected) and prognosis (probability of developing a certain outcome in the future). (1,2) These studies develop, validate, or update a multivariable prediction model, wherein multiple […]

13Aug 2018

Network meta-analysis (NMA) is a type of meta-analysis that adds an additional variable to a meta-analysis, and instead of a simple summation of trials that have evaluated the same treatment, several different treatments are compared by statistical inference.1 NMA is also referred to as mixed treatments comparison or multiple treatments comparison meta-analysis.2,3,4 It was recognised […]

24Jul 2018

Traditionally, systematic reviews are considered as the gold standard to inform clinical practice and policy decisions. However, systematic reviews are resource and time intensive. The time factor has been identified as a barrier to implementing results from evidence synthesis, as a result of an incongruence between the time required to produce a full systematic review […]