In the ever-evolving landscape of scientific research and evidence synthesis, the demand for timely, comprehensive, and reliable information has never been greater. Decision-makers, healthcare professionals, and researchers seek up-to-the-minute insights […]
The bedrock of evidence-based decision-making rests on the integrity of systematic reviews, which rely on the credibility of the studies they encompass. While bias assessment and risk of bias evaluation […]
Meta-analysis is crucial in evidence-based medicine as it combines data from multiple studies for more precise treatment effect estimates. However, when head-to-head clinical trials directly comparing treatments are scarce, Indirect […]
A well-conducted systematic review and meta-analysis can be invaluable to help clinicians stay up-to-date on current evidence-based medicine.(1) However, systematic reviews and meta-analyses often tend to be highly focussed on […]
A systematic literature review (SLR) is considered the highest form of evidence due to its rigorous approach through which every relevant piece of published or unpublished literature that is currently […]
Systematic literature reviews (SLR) are a crucial tool to identify high-quality evidence for research, policy, and practice. The success of SLRs heavily relies on the performance of the literature search […]
Clinical prediction models (CPMs) are statistical models that use patient characteristics and clinical variables to estimate the probability of a particular health outcome, such as a disease or adverse event. […]
The cost of prescription drugs is a significant burden on patients and the healthcare system, especially in countries such as the USA. High drug prices can strain government programs, such […]
Meta-analyses summarize data from head-to-head trials to evaluate pairs of treatments that have been directly compared.[1] However, in certain circumstances, multiple therapies are of interest, and no data is available […]