Drug prices in the US are the highest in the world, which necessitate new or alternate payment approaches. For instance, the new treatments for hepatitis C virus (HCV) infection are highly effective and very expensive at the same time, at least from the view of many payers, physicians, and patients. Even 5 years after these […]
Today’s era of risk based, precision and personalized medicine demands clinical prediction models. Prediction modelling studies focus on two kinds of outcomes, viz. diagnosis (probability of a condition that is undetected) and prognosis (probability of developing a certain outcome in the future). (1,2) These studies develop, validate, or update a multivariable prediction model, wherein multiple […]
Clinical trials lay the foundation for the biomedical research enterprise. They not only assess the applicability of innovative laboratory findings in humans, but also generate robust evidence on treatments and/or preventive interventions in routine clinical care. Clinical trials also directly engage human participants, who trust the investigators to maintain utmost scientific as well as ethical […]
Artificial intelligence (AI) has no universally agreed definition. It roughly includes computing technologies that are similar to processes related to human intelligence; for e.g. reasoning, learning and adaptation, sensory understanding, and interaction. (1,2) At present, most AI applications are limited, since they can only perform specific tasks or solve pre-defined problems. (3) Recently, AI has […]
An excellent population health management approach considers multiple aspects of health, such as sufficiency of medical care, public health interventions, social and physical environments and related services, genetics, and individual behavior. (1) Data from multiple sources can be used to conduct population health management programs and to assess their value. In addition to these diverse […]
Maintaining a record of patients’ medical charts required a lot of physical labour before electronic medical/health records (EMRs/EHRs) became a routine. This physical work provided a greater chance of human error and overlooked information and eventually, irregular maintenance of records. There was a fair chance of 5 out of 15 charts for a clinic day […]
Real-world evidence (RWE) research is gaining significant importance in biopharmaceutical product development as well as its commercialization. The increasing need of the industry to seek broader information about the safety and effectiveness in the real-world setting, which typically impacts the ensuing reimbursement and utilization of new products, is determined by regulators, public and private payers, […]
India is in the middle of health transformation. Although infectious diseases like tuberculosis, malaria, dengue, H1N1 pandemic influenza and antimicrobial resistance continue to pose health and economic burden, the country is also facing challenges with chronic non-communicable diseases, such as cardiovascular diseases, diabetes, cancer; which are the leading cause of mortality. Social and economic determinants […]
The discipline of ‘health economics’ has significantly progressed to become more inclusive, beginning with only cost-benefit analyses of public health programs, such as vaccinations, to evolving into a large area of health technology assessments (HTA). Cost-effectiveness analyses are a routine practice in HTA and are performed virtually for every new health technology. Healthcare industry as […]
